BIFIDOBACTERIUM LACTIS Bl-04^®

Introduction

B. lactis Bl-04® is a human isolate long considered safe and suitable for human consumption. Known for its excellent stability, Bl-04® has been present in a variety of foods and supplements for decades.  It has also been shown to survive passage through the human intestine.^1,2 Bl-04® studies suggest it mechanistically modulates the immune system, and clinical data supports the use of this strain for Immune Health.^3,4  With more than 24 clinical trials, Bl-04® has also been studied in combination with other strains, including NCFM®, Bi-07®, and Lpc-37® as part of the HOWARU® Restore blend for Digestive Health.⁵

REFERENCES:
1. Bartosch S, Woodmansey EJ, Paterson JC, McMurdo ME, Macfarlane GT. Microbiological effects of consuming a synbiotic containing Bifidobacterium bifidum, Bifidobacterium lactis and oligofructose in elderly persons, determined by real-time polymerase chain reaction and counting of viable bacteria. Clin Infect Dis. 2005;40:28-37. 2. Ouwehand AC, Nermes M, Collado MC, et al. Specific probiotics alleviate allergic rhinitis during the birch pollen season. World J Gastroenterology. 2009;15. 3. Turner R, Woodfolk J, Borish L, et al. Effect of probiotic on innate inflammatory response and viral shedding in experimental rhinovirus infection – a randomised controlled trial. Beneficial Microbes. 2017;8:207-215. 4. West NP, Horn PL, Pyne DB, et al. Probiotic supplementation for respiratory and gastrointestinal illness symptoms in healthy physically active individuals. Clin Nutr. 2014;33:581-587. 5. Ouwehand AC, DongLian C, Weijian X, et al. Probiotics reduce symptoms of antibiotic use in a hospital setting: a randomized dose response study. Vaccine. 2014;32:458-463.